Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART |
| Enrichment Score (ES) | 0.6567817 |
| Normalized Enrichment Score (NES) | 1.5967687 |
| Nominal p-value | 0.0045351475 |
| FDR q-value | 0.28555027 |
| FWER p-Value | 0.923 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PRKACB | 4210170 | 9 | 6.062 | 0.2488 | Yes | ||
| 2 | PRKAR1A | 3450369 | 145 | 3.872 | 0.4008 | Yes | ||
| 3 | VEGFA | 2940338 | 505 | 2.707 | 0.4928 | Yes | ||
| 4 | GNB1 | 2120397 | 750 | 2.237 | 0.5717 | Yes | ||
| 5 | PDPK1 | 6650168 | 815 | 2.154 | 0.6568 | Yes | ||
| 6 | PRKAR2A | 2340136 | 2520 | 0.664 | 0.5924 | No | ||
| 7 | PRKAR2B | 3130593 5220577 | 2715 | 0.577 | 0.6057 | No | ||
| 8 | GUCY2C | 110411 6110156 | 3748 | 0.228 | 0.5595 | No | ||
| 9 | SLC7A1 | 2450193 2710241 | 4280 | 0.137 | 0.5365 | No | ||
| 10 | PLCG1 | 6020369 | 4678 | 0.098 | 0.5192 | No | ||
| 11 | PRKG1 | 4120671 | 4925 | 0.082 | 0.5093 | No | ||
| 12 | GUCY1A3 | 110253 2640735 4070037 | 4982 | 0.078 | 0.5095 | No | ||
| 13 | FLT4 | 1240292 6350707 | 5098 | 0.072 | 0.5063 | No | ||
| 14 | GNGT1 | 5220156 | 5851 | 0.044 | 0.4676 | No | ||
| 15 | PIK3CA | 6220129 | 5960 | 0.041 | 0.4634 | No | ||
| 16 | PRKAR1B | 6130411 | 6343 | 0.030 | 0.4441 | No | ||
| 17 | GUCY2F | 2450309 | 6429 | 0.029 | 0.4407 | No | ||
| 18 | CHRNA1 | 1170025 3610364 5220292 | 7067 | 0.016 | 0.4071 | No | ||
| 19 | AKT1 | 5290746 | 7382 | 0.010 | 0.3906 | No | ||
| 20 | PDE3A | 380068 | 8076 | -0.002 | 0.3533 | No | ||
| 21 | RYR2 | 2760671 | 8449 | -0.008 | 0.3337 | No | ||
| 22 | KDR | 3610286 | 9238 | -0.022 | 0.2921 | No | ||
| 23 | CAMK2B | 2760041 | 9655 | -0.030 | 0.2710 | No | ||
| 24 | PIK3R1 | 4730671 | 9937 | -0.035 | 0.2573 | No | ||
| 25 | CHRM1 | 4280619 | 10176 | -0.041 | 0.2462 | No | ||
| 26 | CAV1 | 870025 | 10215 | -0.041 | 0.2458 | No | ||
| 27 | GUCY1A2 | 1660441 | 10559 | -0.049 | 0.2294 | No | ||
| 28 | GNAQ | 430670 4210131 5900736 | 11427 | -0.072 | 0.1856 | No | ||
| 29 | KNG1 | 6400576 6770347 | 12540 | -0.120 | 0.1307 | No | ||
| 30 | GUCY1B2 | 2120128 | 12578 | -0.122 | 0.1337 | No | ||
| 31 | GUCY1B3 | 2970020 | 13008 | -0.152 | 0.1169 | No | ||
| 32 | BDKRB2 | 4780706 | 13246 | -0.169 | 0.1111 | No | ||
| 33 | FLT1 | 3830167 4920438 | 13370 | -0.179 | 0.1118 | No | ||
| 34 | HSP90AA1 | 4560041 5220133 2120722 | 13408 | -0.182 | 0.1173 | No | ||
| 35 | NOS3 | 630152 670465 | 14193 | -0.280 | 0.0866 | No | ||
| 36 | PRKG2 | 1110465 | 15316 | -0.538 | 0.0483 | No | ||
| 37 | PDE3B | 2030563 | 15635 | -0.656 | 0.0582 | No | ||
| 38 | PDE2A | 6100504 | 16468 | -1.104 | 0.0588 | No | ||
| 39 | TNNI1 | 3710040 | 16836 | -1.380 | 0.0958 | No |
